Posts Tagged ‘Italy’

• The Truth About Red Wine and Heart Disease?

  Date: 2007.12.19 | Category: Heart Tips | Response: 0

  Red Wine, Heart Disease, Hungry Sharks and Knights in Shining Armor

  What is so special about wine? What is it that makes it potentially more protective against coronary heart disease, and perhaps other diseases, that other forms of alcohol?

  In recent years, scientists have concluded without doubt that many human diseases such as heart disease, cancer and the aging process is caused or stimulated by a ravenous group of chemicals called free radicals. These highly charged little villains prowl the body and attack healthy cell membranes through a process that is called oxidation. In this scenario, there is however a knight in shining armor that jumps to the rescue and purges these ever hungry little killers. The name of our crusader is antioxidants.

  Without getting too technical, the oxidation process in our bodies is crucial for health, without it, for instance, we would not be able to extract energy from our food. But if there are too many free radicals in our bodies this can be harmful.

  Our body has its own defenses against free radicals, in the form of enzymes that are able to turn the hungry little sharks into harmless water. However, sometimes our bodys natural defense mechanisms cant cope. Other times, external events can cause huge increases of free radicals within our bodies, such as x-rays, cigarette smoke and exposure to toxic substances. At times, this surge of free radicals can swamp our defenses and illnesses such as radiation sickness may take place.

  So what does all this have to do with heart disease?

  Low density lipoproteins, commonly know as bad LDL, can penetrate and gather against the inner walls of our arteries, under certain conditions, forming fatty streaks and plaque. Taken alone, LDL particles arent so dangerous it seems, however, when attacked by free radicals they turn into dangerous and somewhat aggressive cells, capable of actually penetrating and harming the smooth inner walls of our arteries. This process is called oxidation. Oxidized LDL is known to be the culprit in stimulating atherosclerosis, heart disease and stroke.

  Antioxidants, as the name suggests (anti-oxidants) can help stop the oxidation process, which are the results of free radicals doing their stuff. Most antioxidant research has been carried out on vitamins (A, E, beta carotene) but quite a lot of work has also been done on the healthy benefits of red wine. While most research on red wine has been done in relation to coronary heart disease, it seems that the benefits of wine dont stop there.

  Red wine and Coronary Heart Disease

  Red wine contains a wide range of flavanoids; these are the chemicals that give the wine its particular taste and character, making one different from another. Many of these flavanoids act like antioxidants. Perhaps the forerunner of wine research was carried out by a certain Serge Renaud, who discovered the French Paradox, which suggested that wine was the decisive factor in protecting the people in southern France from their very high fat diets and ultimately coronary heart disease. Even if these people do eat large quantities of high fat cheese, pt, and salami they have some of the lowest rates of heart disease in the world.

  Another study, statistical rather than practical, by a Professor Grey of the University of Bern in Switzerland focused on the low, medium and high coronary heart disease (CHD) mortality figures of the World Health Organization.

  What did he find? Well from among the high mortality areas were Finland and Scotland, the middle areas included Ireland, and the low CHD areas included Spain, Italy and France. He then compared heart attack rates with antioxidant levels in blood samples taken from men living in those areas.

  What he found was very interesting, the results showed that high antioxidant levels, in particular vitamin E, coincided with low death rates of heart disease. Moreover, his results showed that vitamin E levels were 94% more accurate in predicting CHD rates than were cholesterol levels or blood pressure figures! Apart from diet, the high CHD regions drink very little, if any wine, whereas the low regions traditionally accompany their meals most days with wine.

  It certainly seems strange that two much studied cities; Glasgow in Scotland and Toulouse in France show many similarities and yet many differences. The inhabitants of both cities eat tremendous amounts of high fat foods, traditionally take little exercise and drink alcohol. The surprising difference is that while the people of Glasgow have one of the highest rates of CHD in the world, the fortunate people of Toulouse have one of the lowest. Traditionally beer and spirits are the preferred drinks in Glasgow, while the folks in Toulouse drink red wine.

  It has also been suggested that drinking in moderation together with meals is beneficial, while binge drinking at bars in the evening is harmful. It seems the southern Europeans dont drink for the alcohol buzz, but just as a pleasant accompaniment to their meals.

  At first the large heart institutions such as the American College of Cardiology and the American Heart Association ignored both antioxidants and frowned upon wine. While it is clear that it could be potentially dangerous for a physician to recommend his patients start drinking alcohol, it is also strange that they pretended for so many years to ignore the evidence. Well, now even if they dont promote the taking of vitamin pills; antioxidants and free radicals are now recognized.

  However, according to the AHA There is no scientific proof that drinking wine or any other alcoholic beverage can replace conventional measures … No direct comparison trials have been done to determine the specific effect of wine or other alcohol on the risk of developing heart disease or stroke. Just ask yourself who would pay for such studies. Clinical Trials have the purpose of showing one thing to be better than another, or whether a certain substance is beneficial to health. The costs of clinical trials is so high that only the pharmaceutical industry have the financial clout to invest in them invest is the correct word. What a surprise.

  About the Author

  http://www.allabout-heart-disease.com the site that tells you how it is, about getting your life back and living it to the full! Articles, tips, advice and the latest news on how to take care of your heart. You can get articles like this in your mailbox each month by submitting to our eZine The Webs Heart at: http://www.allabout-heart-disease.com/webs-heart-subscribe.html

  Written By: Nicholas Webb

• Treatment of Heart Disease with Coenzyme Q10

  Date: 2007.11.29 | Category: Heart Tips | Response: 0

  Since its discovery in the late 1950s Coenzyme Q10 (CoQ10) has received much attention as a necessary compound for proper cellular function. It is the essential coenzyme necessary for the production of ATP (adenosine triphosphate) upon which all cellular functions depend. Without ATP our bodies cannot function properly. Without CoQ10, ATP cannot function. This connection has made CoQ10 a very important object of study in relation to chronic disease. In many cases the presence of chronic disease is associated with inadequate levels of CoQ10. But no area of study has received more attention than the relation between CoQ10 and heart disease. That is because CoQ10 is believed to be of fundamental importance in cells with high metabolic demands such as cardiac cells. A further reason the connection of heart disease and CoQ10 has gained so much attention is because heart conditions of many kinds are associated with chronically low CoQ10 levels.

  CoQ10 is highly concentrated in heart muscle cells because of their high energy requirements. Add this to the fact that heart disease is the number one killer in developed and developing countries and one can see why the bulk of scientific research on CoQ10 has been concerned with heart disease. Specifically, studies on congestive heart failure have demonstrated a strong correlation between the severity of heart failure and the degree of CoQ10 deficiency. The lower the levels of CoQ10 in the heart muscles the more severe the heart failure. If indeed CoQ10 deficiency is a primary cause of congestive heart failure then, in such cases, the remedy is simple and cost effective; CoQ10 supplementation.

  Congestive heart failure is a condition where the heart does not pump effectively resulting in an accumulation of fluid in the lungs. Symptoms may include shortness of breath, difficulty breathing when lying flat and leg or ankle swelling. Causes include chronic hypertension, cardiomyopathy (primary heart disease) and myocardial infarction (irreversible injury to heart muscles). Heart muscle strength is measure by the ejection fraction which is a measure of the fraction of blood pumped out of the heart with each beat. A low ejection fraction indicates a weak heart.

  Several trials have been conducted involving patients with enlarged weak heart muscles of unknown causes. For those of you who like difficult phrases this condition (or variety of conditions) is known as idiopathic dilated cardiomyopathy. In these trials CoQ10 supplementation was compared to placebo effects. Standard treatments for heart failure were not discontinued. The results were measured by echocardiography (a diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures). The overall results of CoQ10 supplementation demonstrated a steady and continued improvement in heart function as well as steady and continued reduction in patient symptoms including fatigue, chest pains, palpitations and breathing difficulty. Patients with more establish and long-term cases showed gradual improvement but did not gain normal heart function. Patients with newer cases of heart failure demonstrated much more rapid improvement often returning to normal heart function.

  Papers numbering in the hundreds from eight different symposia have been written and presented on the effects of CoQ10 on heart disease. International clinical studies have also been conducted in the United States, Japan, Germany, Italy and Sweden. Together these studies and the papers that have been derived from them demonstrate significant improvement in heart muscle function while causing no adverse effects.

  One particular area of study involves diastolic dysfunction which is one of the earliest signs of myocardial failure. Diastole is the phase of the cardiac cycle when the heart is filled with returning blood. Because this phase requires more cellular energy than the systolic phase (when the blood is pushed out of the heart) it is more dependent on CoQ10. Diastolic dysfunction is a stiffening of the heart muscle which naturally restricts the hearts ability to pump. This condition is associated with many cardiac disorders. Hypertension is among these disorders. As the heart muscles become stiff there is often a corresponding rise in blood pressure. When the diastolic dysfunction is reversed, blood pressure tends to lower as well. In one study involving 109 patients with hypertension, CoQ10 supplementation was added to normal hypertension treatments. In an average of 4.4 months 51% of the patients were able stop using at least one blood pressure lowering medication. Some were able to stop using up to three medications. Another study produced similar results. In that study 43% of 424 patients were able to stop using between one and three cardiovascular drugs because of CoQ10 supplementation.

  These examples are just a drop in the bucket. Diastolic dysfunction (and by proxy, hypertension) includes only a small sampling of heart conditions that respond favorably to CoQ10 supplementation. Other areas of research show great promise for CoQ10 treatments. Among these are cancer and AIDS. But such conditions are beyond the scope of this essay. CoQ10 is essential to the proper functioning of all cell types. It is not surprising, therefore, to find a diverse number of diseases that respond favorably to CoQ10 supplementation. Since all metabolically active tissues are highly sensitive to CoQ10 deficiency, we can expect to see CoQ10 research expand to many other areas of chronic diseases.

  http://www.optimal-heart-health.com/coq10.html

  About the Author

  Greg has degrees in science, divinity and philosophy and is currently an I.T. developer.

  Written By: Greg Post