Posts Tagged ‘cardiomyopathy’
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What is Heart Disease?
Cardiovascular disease is a very broad term. Cardiovascular disease refers to diseases of the heart (cardio) and diseases of the blood vessels (vascular), hence cardio-vascular disease. However, diseases affecting the heart are referred to as heart disease.
The term heart disease is a very broad term. Problems can arise within the heart muscle, arteries supplying blood to the heart muscle, or the valves within the heart that pump blood in the correct direction. Understanding the differences between each disease of the heart can help with the confusing applications of the term heart disease. Coronary artery disease or CAD is the most common type of heart disease and the leading cause of death in both genders in the U.S. Coronary artery disease affects the arteries supplying blood to the heart muscle. These coronary arteries harden and narrow due to the buildup of a waxy cholesterol, fatty substance referred to as plaque.
This plaque buildup is known as atherosclerosis. The increase in plaque buildup causes the coronary arteries to become narrower. This will cause blood flow to become restricted, decreasing the amount of oxygen delivered to the heart muscle. Decreasing the amount of oxygen supplied to the heart muscle can cause angina (chest pain) and lead to a heart attack. Coronary artery disease over time can weaken the heart muscle contributing to heart failure and arrhythmias (abnormal heart rhythms).
Coronary heart disease is another confusing type of heart disease. Coronary heart disease is not the same thing as coronary artery disease. While coronary artery disease refers to the coronary arteries, coronary heart disease refers to the diseases of the coronary arteries and resulting complications. This includes such complications such as chest pain, a heart attack, and the scar tissue caused by the heart attack. Understanding this subtle difference between the two may impress your cardiologist.
Cardiomyopathy is a disease affecting the muscle of the heart. Cardiomyopathy can be genetic or caused by a viral infection. Cardiomyopathy can be classified as primary or secondary. Primary cardiomyopathy is attributed to a specific cause (hypertension, congenital heart defects, heart valve disease). Secondary cardiomyopathy is attributed to specific causes (diseases affecting other organs).
There are three main types of cardiomyopathy. Dilated cardiomyopathy is enlargement and stretching of the cardiac muscle. Hypertrophic cardiomyopathy causes thickening of the heart muscle. Restrictive cardiomyopathy causes the ventricles of the heart to become excessively rigid causing blood flow to the ventricles to be difficult between heartbeats.
Valvular heart disease is a disease that affects the valves of the heart. Valves within the heart keep the blood flowing in the correct direction. Damage to valves can be caused by a variety of conditions leading to regurgitation or insufficiency (leaking valve), prolapse (improper closing of the valve), or stenosis (narrowing of the valve). Valvular heart disease can be genetic. Valvular heart disease can also be caused by certain infections such as rheumatic fever, and certain medications or radiation treatments for cancer.
The pericardium is a sac that encompasses the heart. Pericardial disease is inflammation (pericarditis), stiffness (constrictive pericarditis), or fluid accumulation (pericardial effusion) of the pericardium. Pericardial disease can be caused by many things such as occurring after a heart attack.
Congenital heart disease is a form of heart disease that develops before birth. Congenital heart disease is an extremely broad term. However, these diseases usually affect the formation of the heart muscle, chambers, or valves. A few examples include coarctation or a narrowing of a section of the aorta; atrial or ventricular septal defect is referred to as holes in the heart. Congenital heart disease should be classified more accurately as an inborn defect that occurs in around 1% of births. Congenital heart disease may be inherited (heredity), or caused by certain infections such as German measles contracted while pregnant. However, researchers are currently studying factors that may cause congenital heart disease.
Heart failure is another type of heart disease characterized by the hearts inability to effectively pump enough blood to the bodys organs and tissues. When the bodys vital organs do not receive enough blood flow certain signs and symptoms can occur such as shortness of breath, fatigue, and fluid retention. Congestive heart failure is a type of heart failure that leads to fluid buildup in the body. It is important to note that not all heart failure is congestive. Heart failure may result from other cardiovascular diseases such as cardiomyopathy or coronary heart disease. Heart failure may come on suddenly or develop over many years.
The month of February is the National Heart Disease awareness month. However, heart disease awareness should be each and every day. With staggering statistics, awareness begins with understanding the different types of heart disease. A diet and lifestyle that is conducive to heart health can mean the difference between life and being a statistic.
ABOUT THE AUTHOR
Kristy Haugen is a mother and an experienced nurse. She also has a bachelor degree in Biology and Chemistry. She writes to inform consumers about nutrition and health topics. Learn more about weight loss supplements at http://weightlosssupplements.vitaminmaniac.com . Learn more about vitamins and your health at http://blog.vitaminmaniac.com .
Written By: Kristy Haugen
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Treatment of Heart Disease with Coenzyme Q10
Since its discovery in the late 1950s Coenzyme Q10 (CoQ10) has received much attention as a necessary compound for proper cellular function. It is the essential coenzyme necessary for the production of ATP (adenosine triphosphate) upon which all cellular functions depend. Without ATP our bodies cannot function properly. Without CoQ10, ATP cannot function. This connection has made CoQ10 a very important object of study in relation to chronic disease. In many cases the presence of chronic disease is associated with inadequate levels of CoQ10. But no area of study has received more attention than the relation between CoQ10 and heart disease. That is because CoQ10 is believed to be of fundamental importance in cells with high metabolic demands such as cardiac cells. A further reason the connection of heart disease and CoQ10 has gained so much attention is because heart conditions of many kinds are associated with chronically low CoQ10 levels.
CoQ10 is highly concentrated in heart muscle cells because of their high energy requirements. Add this to the fact that heart disease is the number one killer in developed and developing countries and one can see why the bulk of scientific research on CoQ10 has been concerned with heart disease. Specifically, studies on congestive heart failure have demonstrated a strong correlation between the severity of heart failure and the degree of CoQ10 deficiency. The lower the levels of CoQ10 in the heart muscles the more severe the heart failure. If indeed CoQ10 deficiency is a primary cause of congestive heart failure then, in such cases, the remedy is simple and cost effective; CoQ10 supplementation.
Congestive heart failure is a condition where the heart does not pump effectively resulting in an accumulation of fluid in the lungs. Symptoms may include shortness of breath, difficulty breathing when lying flat and leg or ankle swelling. Causes include chronic hypertension, cardiomyopathy (primary heart disease) and myocardial infarction (irreversible injury to heart muscles). Heart muscle strength is measure by the ejection fraction which is a measure of the fraction of blood pumped out of the heart with each beat. A low ejection fraction indicates a weak heart.
Several trials have been conducted involving patients with enlarged weak heart muscles of unknown causes. For those of you who like difficult phrases this condition (or variety of conditions) is known as idiopathic dilated cardiomyopathy. In these trials CoQ10 supplementation was compared to placebo effects. Standard treatments for heart failure were not discontinued. The results were measured by echocardiography (a diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures). The overall results of CoQ10 supplementation demonstrated a steady and continued improvement in heart function as well as steady and continued reduction in patient symptoms including fatigue, chest pains, palpitations and breathing difficulty. Patients with more establish and long-term cases showed gradual improvement but did not gain normal heart function. Patients with newer cases of heart failure demonstrated much more rapid improvement often returning to normal heart function.
Papers numbering in the hundreds from eight different symposia have been written and presented on the effects of CoQ10 on heart disease. International clinical studies have also been conducted in the United States, Japan, Germany, Italy and Sweden. Together these studies and the papers that have been derived from them demonstrate significant improvement in heart muscle function while causing no adverse effects.
One particular area of study involves diastolic dysfunction which is one of the earliest signs of myocardial failure. Diastole is the phase of the cardiac cycle when the heart is filled with returning blood. Because this phase requires more cellular energy than the systolic phase (when the blood is pushed out of the heart) it is more dependent on CoQ10. Diastolic dysfunction is a stiffening of the heart muscle which naturally restricts the hearts ability to pump. This condition is associated with many cardiac disorders. Hypertension is among these disorders. As the heart muscles become stiff there is often a corresponding rise in blood pressure. When the diastolic dysfunction is reversed, blood pressure tends to lower as well. In one study involving 109 patients with hypertension, CoQ10 supplementation was added to normal hypertension treatments. In an average of 4.4 months 51% of the patients were able stop using at least one blood pressure lowering medication. Some were able to stop using up to three medications. Another study produced similar results. In that study 43% of 424 patients were able to stop using between one and three cardiovascular drugs because of CoQ10 supplementation.
These examples are just a drop in the bucket. Diastolic dysfunction (and by proxy, hypertension) includes only a small sampling of heart conditions that respond favorably to CoQ10 supplementation. Other areas of research show great promise for CoQ10 treatments. Among these are cancer and AIDS. But such conditions are beyond the scope of this essay. CoQ10 is essential to the proper functioning of all cell types. It is not surprising, therefore, to find a diverse number of diseases that respond favorably to CoQ10 supplementation. Since all metabolically active tissues are highly sensitive to CoQ10 deficiency, we can expect to see CoQ10 research expand to many other areas of chronic diseases.
http://www.optimal-heart-health.com/coq10.html
About the Author
Greg has degrees in science, divinity and philosophy and is currently an I.T. developer.
Written By: Greg Post
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Congestive Heart Failure And CoQ10
Since the 1960s there have been numerous controlled clinical trials concerning the relationship between congestive heart failure and Coenzyme Q10 (CoQ10). As its name implies CoQ10 is a coenzyme that is necessary for the proper functioning of other substances, one of the most important of which is ATP (adenosine triphosphate). ATP is necessary for the production of cellular energy. By proxy CoQ10 is likewise essential for this process.
Clinical trials have attempted to study the relationship between CoQ10 and many chronic diseases including, but not limited to, heart disease, cancer and AIDS. But heart disease has gained the most attention; congestive heart failure being one of the primary subjects. Because heart muscle cells require so much energy to function and CoQ10 is at the core of the cellular energy process it makes sense to suspect that congestive heart failure might be linked to CoQ10 deficiency. With that theory in mind many studies like the ones that follow have been conducted. These trials have been presented in this essay in thumbnail format.
One early Japanese trial (1972) involved 197 patients with varying levels of severity of cardiac failure. The study reported significant improvement of cardiac function supplementing with 30 mg per day of CoQ10. Another Japanese study demonstrated similar results with 38 patients also supplementing with 30 mg. In 1985 a U.S. clinical study prescribed daily supplementation with 100 mg of the coenzyme for treatment periods of three months for patients with low ejection fraction measurements. The ejection fraction is the measure of the hearts ability to pump blood. A low ejection fraction is a classic symptom of congestive heart failure. Again, significant improvements in heart function were reported. Other clinical trials followed prescribing the same level of supplementation with similar results.
Studies in the early 1990s showed improvement for patients suffering from ischemic cardiomyopathy (a low oxygen state usually due to obstruction) with supplemental levels of 200 mg per day. Supplementing with 100 mg per day demonstrated improvement for patients suffering from idiopathic dilated cardiomyopathy, an enlarged heart syndrome of unknown cause.
One of the largest trials of the 1990s involves 641 patients randomly divided into two groups. The first group received a placebo. The other group received CoQ10 supplements. During the one-year follow-up period 118 patients in the placebo group were hospitalized for heart failure compared to 73 in the group that received the supplements.
All of the preceding trials were relatively short-term studies. The level of improvement among patients varied depending on how long they had been suffering from some aspect of congestive heart failure. Through the years it has become increasing clear that the greatest improvements were shown in patients that had suffered from their condition the least amount of time. In other words, the longer a person had been suffering from the disease before he or she received CoQ10 treatments the less improvement was demonstrated. People who had received treatments early in the development of the disease showed the most dramatic improvement often returning to normal heart function. Long-term sufferers received less relief and were less likely to return to full heart function. Whatever the reasons for this disparity in health improvement, it demonstrates the importance of receiving treatment as early as possible.
But what about long-term studies? Do they show the same marked improvement with similar treatment? In the short-term trials it was apparent that even high level supplementing with CoQ10 seemed to produce no ill effects. In order to determine if this is only true for short durations a number of long-term studies were conducted.
In 1990 observations were published concerning 126 patients with dilated cardiomyopathy. Unlike previously noted studies this one followed the patients progress for six years. Long-term benefits from CoQ10 supplementing were noticed with no harmful side effects. Similar observations were made in a trial involving 2,664 patients treated with CoQ10 at levels up to 150 mg per day.
A 1994 study involving 424 patients with a variety of myocardial (refers to the heart’s muscle mass) diseases. Among these conditions were the following: Valvular heart disease (pertaining to dysfunction of heart valves), hypertension, diastolic dysfunction (failure of the heart to properly refill itself with blood), dilated cardiomyopathy (group of disorders where the heart muscle is weakened and enlarged and cannot pump effectively) and ischemic cardiomyopathy (low oxygen state usually due to obstruction of the arterial blood supply). Patients were treated with an average of 240 mg of CoQ10 daily during their treatment period. They were then followed-up for up to eight years with an average follow-up period of 18 months. Overall results demonstrated measurable cardiac improvements in one month with maximum improvements at about six months. With continued CoQ10 treatment the improvement in most patients was sustained. However, discontinuing the treatment usually resulted in a decline of cardiac function with eventual return to pre-treatment conditions.
As always in the medical community many more studies will need to be conducted to determine the future of CoQ10 treatment. However, the research to date seems to support CoQ10 as a viable treatment for many diseases that are caused or exacerbated by inadequate production of cellular energy.
http://www.optimal-heart-health.com/coq10.html
About the Author
Greg has degrees in science, divinity and philosophy and is currently an I.T. developer.
Written By: Greg Post
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Understanding Heart Disease
UNDERSTANDING THE BASICS OF YOUR HEART AND HEART DISEASE
Understand the basics associated with your heart and blood vessels. Here you will get an understanding of all the different types of cardiovascular disease that can be confusing. Get a basic overview of cardiovascular disease and the conditions that can affect your heart and blood vessels.
You probably hear a lot about preventing heart disease. But maybe you’re not sure what heart disease is. Is it the same thing as cardiovascular disease, coronary artery disease or other heart terms you sometimes see?
With many medical terms related to the heart and blood vessels, it’s no wonder you may be puzzled or confused. Here you will have a chance to brush up on some basic terms about cardiovascular disease (CVD) that can help you stay more informed. This can then help you when you’re watching the news or meeting with your doctor.
The first term to know is Cardiovascular Disease or CVD. CVD is a broad term. CVD is a large collection of diseases and conditions.
If you want to be technical, CVD refers to any disorder in any of the various parts of your heart system. Your cardiovascular system consists of your heart and all the blood vessels throughout your whole body.
Cardiovascular disease has two main mechanisms:
Diseases of the Heart (cardio)
Diseases of the Blood Vessels (vascular)
Everything from an aneurysm to a heart attack to varicose veins are all types of CVD. You may be born with a type of CVD (congenital) or you may acquire others later on in life possibly from a lifetime of unhealthy habits, lack of exercise, smoking, and other factors.
Here’s a closer look at the two mechanisms of cardiovascular disease.
Diseases of the Heart
The diseases and conditions that affect the heart are in a group known as heart disease. The heart consists of a muscle that pumps blood. Arteries supply blood to the heart muscle, and the valves make sure that the blood within the heart is pumped in the right direction. Problems can occur in any of these areas.
Just like CVD, Heart Disease is a broad term.
Here are the specific types of heart disease:
**Coronary Artery Disease (CAD)
**Coronary Heart Disease (CHD)
**Cardiomyopathy
**Valvular heart disease
**Pericardial disease
**Congenital heart disease
**Heart failure (CHF)
Diseases of the Blood Vessels
Blood vessels are in basic terms hollow tubes that carry blood to the organs and tissues throughout your body.
There are 4 basic types of blood vessels:
Arteries. These blood vessels carry oxygenated blood to all parts of the body
Veins. These blood vessels carry deoxygenated blood back to your heart. That is why they have a bluish cast to their color
Capillaries. These are tiny vessels that connect your arteries and veins.
Lymphatics. Fluid that leaks out of your capillaries in order to bathe your cells.
Here are some types of blood vessel disorders:
**Arteriosclerosis and atherosclerosis
**High blood pressure (HBP) or Hypertension (HTN)
**Stroke
**Aneurysm
**Peripheral Arterial Disease (PAD) and claudication
**Vasculitis
**Venous incompetence
**Venous thrombosis or blood clot
**Varicose veins
**Lymphedema
Heart Disease is a serious condition. Watch your fatty food intake, smoking, as well as your sweet tooth intake. Both can cause serious heart problems.
It is best to start out slow when changing your diet. Eating fresh fruits and vegetables is a great way to start.
About the author:
F. Kuhn, RN specializing in cardiac and diabetic teaching
http://www.heartnewscenter.com
http://www.diabetestestingcenter.com
Written By: F. Kuhn, RN
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CO-Q10 for a Healthy Heart
Coenzyme Q10 (also known as Co-Q10, Vitamin Q or ubiquinone) is a compound that is made naturally in the body. It is also found in all living organisms and most foods contain traces of it as well. The highest amounts are found in the heart, liver, kidneys, and pancreas, with the lowest amounts found in the lungs. It is needed for the proper functioning of enzymes (thus the reason for the name “coenzyme”) that are necessary for chemical reactions throughout the body. Coenzymes are a sort of energy sparking catalyst for the cells of the body.
Our bodies could not survive without energy producing Co-Q10. It’s a necessary nutrient needed for the proper functioning of every cell. Without it we would not have enough cellular energy to fuel the physiological reactions we need to survive. As a powerful antioxidant, it also protects the body from free radical damage that can damage important parts of the cell. Several small studies have even shown a benefit for some cancers, possibly because of its immune enhancing effects.
The heart requires the most Co-Q10, calling for a constant supply of energy to pump blood throughout the body. Numerous studies have shown that Co-Q10 can support the cardiovascular system when dealing with such issues as mitral valve prolapse, hypertension, cardiomyopathy, irregular heartbeat, angina and high blood pressure.
Since Coenzyme Q10 assists the body on a cellular level, sufficient stores of this nutrient are needed to fight off illnesses such as chronic fatigue, fibromyalgia, and Parkinson’s disease. Having enough Co-Q10 ensures that you can retain proper muscle function and overall stamina.
This important nutrient is easily depleted by stress, age, illness, exercise, and some drugs. Along with blocking the liver mechanism that manufactures cholesterol, cholesterol-lowering drugs, like Lipitor, Zocor and Pravachol (also known as statins) block the production of Coenzyme Q10. Other drugs such as antidepressants and beta blockers also deplete this important nutrient.
Co-Q10 is essential for the functioning of every cell in our bodies. Again, without it we could not survive. When it drops, so does our cardiovascular health, our immunity and general health. When Co-Q10 levels are boosted, so is our immune systems response. Therefore, taking a look at Co-Q10, may assist you in reversing cardiovascular disease, symptoms of fatigue or generally in enhancing the immune system and fending off disease.
Coenzyme Q10 is a boost to overall health. An aid for…TRUE HEALTHY LIVING!
About the author:
Due to personal health issues we have been researching health & fitness for the last five years. The information we have obtained has helped us and our family members get off pharmaceutical drugs and regain a level of health we had never known. Please visit us at http://www.truehealthyliving.blogspot.com
Written By: D & D @ True Healthy Living
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